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The 16 Biggest Upsets In NCAA Tournament History

6. Santa Clara over Arizona

In 1993, Santa Clara's coach didn't think his team had a prayer. And things looked bleak when Arizona scored 25 straight points. But the underdog, as underdogs do, battled back. Steve Nash and the Broncos became just the second 15 seed to upset a No. 2 in NCAA Tournament history. (AP File Photo)

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