7. George Mason over Connecticut

The 16 Biggest Upsets In NCAA Tournament History

The Patriots became only the second No. 11 seed to reach the Final Four when they upset top-seeded UConn, 86-84, in overtime during the 2006 NCAA Tournament. The Patriots lost their next game to the Florida Gators, who went on to win the national title. (AP File Photo)

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The Not-So-Sweet... When you're talking basketball in the month of March, everything's open for debate. But we think you'll agree with this list of the 16 biggest upsets in NCAA Tournament history.

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16. Arkansas-Lit... Former Notre Dame coach Digger Phelps saw his hopes for a 1986 title run end in the first round when the heavily favored Irish dropped a first-round decision to 14th-seeded Arkansas-Little Rock. (AP File Photo)

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15. Northern Iow... Ali Farokhmanesh's three-pointer in the closing seconds gave unheralded Northern Iowa a second-round upset over top overall seed Kansas in the second round of the 2010 NCAA Tournament. (AP File Photo)

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14. Austin Peay ... No. 14 Austin Peay came in as huge underdogs to a powerful Illinois squad in the 1987 NCAA Tournament. Not believing the Governors could win, ESPN analyst Dick Vitale said he would stand on his head if they pulled off the upset. Well, they did, stunning the Fightin’ Illini in the opening round. Suffice to say, Dickie V didn’t uphold his end of the deal. (AP File Photo)

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13. Valparaiso o... In one of the most memorable finishes in NCAA Tournament history, Valparaiso outlasted Mississippi in a 1998 first-round game that went down to the wire. With the Crusaders down two, Bryce Drew, the son of Valpo coach Homer Drew, nailed a three-pointer at the buzzer to give the Crusaders a 70-69 win and their first NCAA Tournament victory. (AP File Photo)

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12. Davidson ove... Sophomore Stephen Curry scored 25 points in the second half to help Davidson stun Georgetown, 74-70, in the second round of the 2008 NCAA tourney. The Wildcats defeated Wisconsin in the Sweet Sixteen, but lost to the eventual national champion Kansas Jayhawks in the Elite Eight. (AP File Photo)

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11. Princeton ov... In 1996, the defending national champion UCLA Bruins had a favorable first-round game against the Ivy League's Princeton Tigers. However, with the score tied at 41, Princeton's Gabe Lewullis converted a backdoor layup in the waning seconds. (AP File Photo)

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10. Cleveland St... Despite finishing the regular season 27-3, Cleveland State entered the 1986 NCAA tournament as a No. 14 seed. Led by Clinton Ransey, who scored 27 points, the Vikings stunned the heavily favored Hoosiers, 83-79, in the first round. (AP File Photo)

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9. Coppin State ... The No. 15-seed Eagles were 30-point underdogs when they met second-seeded South Carolina in the first round of the 1997 NCAA Tournament. But Danny Singletary led Coppin State to the 78-65 upset. It was the first tournament win in Coppin State's school history. (AP File Photo)

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8. Hampton over ... In 2001, the No. 15 Hampton Pirates were up against a No. 2 Iowa State team featuring future first-round NBA picks Marcus Fizer and Jamaal Tinsley. But it was the Pirates' Tarvis Williams who knocked down a shot with 6.9 seconds left to give Hampton a 58-57 victory. The Cyclones had one last chance to win, but Tinsley missed a lay-in. (AP File Photo)

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7. George Mason ... The Patriots became only the second No. 11 seed to reach the Final Four when they upset top-seeded UConn, 86-84, in overtime during the 2006 NCAA Tournament. The Patriots lost their next game to the Florida Gators, who went on to win the national title. (AP File Photo)

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6. Santa Clara o... In 1993, Santa Clara's coach didn't think his team had a prayer. And things looked bleak when Arizona scored 25 straight points. But the underdog, as underdogs do, battled back. Steve Nash and the Broncos became just the second 15 seed to upset a No. 2 in NCAA Tournament history. (AP File Photo)

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5. Richmond over... In 1991, the Spiders opened the eyes of the college basketball world by becoming the first No. 15 seed to win a first-round game. Richmond upset a Syracuse squad led by coach Jim Boeheim and star Billy Owens, 73-69. (AP File Photo)

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4: Duke over UNL... In 1991, the Duke Blue Devils shocked the UNLV Runnin' Rebels, 79-77, in the Final Four. The upset was truly special because UNLV embarrassed Duke by 30 points in the national title game the season before, and entered this 1991 semifinal game with a perfect record. (AP File Photo)

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3. Texas Western... Texas Western, now UTEP, was the first team to have a starting lineup of five African-American players in 1966. In a tourney field of 22 teams, Western did the unthinkable when it upset national powerhouse Kentucky in the championship game. Their triumphant 1966 season was the basis for the film "Glory Road." (AP File Photo)

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2. Villanova ove... The 1985 championship game between Villanova and Georgetown seemed a lopsided matchup on paper. The Hoyas had future pros in Patrick Ewing, Reggie Williams and David Wingate, and had already defeated Villanova twice in the regular season. The Wildcats kept things close in the second half and ended the game shooting a remarkable 78.6 percent from the floor. The Georgetown dynasty lost once again in the championship game, 66-64. (AP File Photo)

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1. North Carolin... Few expected sixth-seeded N.C. State to beat Houston and Phi Slamma Jamma in the 1983 national championship game. But the game came down to one of the most thrilling finishes in college basketball history when Lorenzo Charles dunked Dereck Whittenburg's missed shot at the buzzer to give Jim Valvano and the Wolfpack a shocking 54-52 victory and the national title. (AP File Photo)

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