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The 16 Biggest Upsets In NCAA Tournament History

8. Hampton over Iowa State

In 2001, the No. 15 Hampton Pirates were up against a No. 2 Iowa State team featuring future first-round NBA picks Marcus Fizer and Jamaal Tinsley. But it was the Pirates' Tarvis Williams who knocked down a shot with 6.9 seconds left to give Hampton a 58-57 victory. The Cyclones had one last chance to win, but Tinsley missed a lay-in. (AP File Photo)

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