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Health.com: 12 Surprising Causes of Depression

Birth Control Pills

Like any medication, the Pill can have side effects. Oral contraceptives contain a synthetic version of progesterone, which studies suggest can lead to depression in some women. The reason is still unknown, says Hilda Hutcherson, MD, clinical professor of obstetrics and gynecology at Columbia University, in New York. "It doesn't happen to everyone, but if women have a history of depression or are prone to depression, they have an increased chance of experiencing depression symptoms while taking birth control pills," Dr. Hutcherson says. "Some women just can't take the Pill; that's when we start looking into alternative contraception, like a diaphragm, which doesn't contain hormones."

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