Eight years after her "Seinfeld" appearance, Megan Mullally landed the role of Karen Walker on the wildly popular show "Will and Grace." She won the Emmy Award for Outstanding Supporting Actress in a Comedy Series in 2000 and 2006 for the part. Mullally, now 55, most recently appeared on the NBC comedy "Parks & Rec" and ABC series "Happy Endings." —XFINITY Entertainment Staff (Photo by D Dipasupil/Getty Images)
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