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MTV Stars Then & Now

Karen Duffy

Then: The model and TV actor joined MTV in the early ‘90s and made an instant impression as the precocious “Duff.”

Now: Following a bout with sarcoidosis of the central nervous system, for which she underwent chemotherapy, Duffy released a well-received autobiography, “Model Patient: My Life As an Incurable Wise-Ass,” and returned to TV. She currently hosts TLC’s “House of Tiny Terrors.” —XFINITY Entertainment Staff (Photos: George De Sota, Theo Wargo, Getty Images)



The opinions expressed are solely those of the author and do not necessarily reflect the views of Comcast.

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