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Show Me the Funny! Hollywood Crack-Ups

40 of 41

John C. Reilly

One of his most mainstream, high profile appearances was custom made for Reilly’s sympathetic everyman charm, co-starring with Will Ferrell as the loyal, left-in-the-dust best friend in “Talladega Nights: The Ballad of Ricky Bobby” (2006). Reilly’s winning comic performance led to first billing in Jake Kasdan and Judd Apatow’s “Walk Hard: The Dewey Cox Story” (2007). Continuing with his resounding success in broad comedies, Reilly would reteam with Ferrell and director Adam McKay in “Step Brothers." (All Movie Guide; Photo by Kristian Dowling/Getty Images)

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