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Hollywood's Biggest Feuds

20 of 23

Isaiah Washington and Patrick Dempsey

Bad blood had been brewing on the set of "Grey's Anatomy" for a while in 2006, but it all came to a head when series stars Isaiah Washington and Patrick Dempsey had a violent backstage blow-up. During the heated exchange, Washington reportedly used a homophobic slur in reference to co-star T.R. Knight. The fallout ultimately resulted in Washington being fired from the show. —XFINITY Entertainment Staff (Photos by Getty Images)

The opinions expressed are solely those of the author and do not necessarily reflect the views of Comcast.

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