Billionaire mogul Howard Hughes, who gained popularity in the late 1920s as a maverick film producer, openly suffered from obsessive-compulsive disorder. In 1957, Hughes locked himself in a dark screening room for four months, watching movie after movie. He emerged dirty and naked, quickly taking residence in a private bungalow at the Beverly Hills hotel. Hughes lived out the rest of his life in hotel rooms, dying in self-imposed seclusion in 1976. —XFINITY Entertainment Staff (Photo by Topical Press Agency/Hulton Archive/Getty Images)
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