Patricia and Rosanna Arquette
The Arquette brood is one of Tinseltown’s largest dynasties, and representing the female side of the family are sisters Patricia and Rosanna. Rosanna, 55, has appeared in a myriad of television and movie roles, including recent spots on “Ray Donovan” and the movie "Draft Day." Patricia, 46, played the lead role on the television series “Medium” from 2005-2011. —XFINITY Entertainment Staff (Photo by Frazer Harrison/Getty Images)
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