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The revelation Catherine Zeta-Jones checked into a clinic for bipolar disorder has brought attention to a condition that can cause dramatic shifts in one's mood, energy, and activity levels. (It's often referred to as manic-depression.) Psychiatrists believe that at least one percent of the population suffers from it. Here, stars who acknowledge having the condition. (Note: There are many luminaries present and past rumored to be bipolar, but there is no conclusive proof.) Above: Zeta-Jones at the Golden Globe Awards in 2011. (ROBYN BECK/AFP/Getty Images/LIFE.com) Visit LIFE: Your World in Pictures